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This is why older patients should receive a reduced dosage of the drug ( 6.2 Strategies to increase bioavailability of taxanes 6.2.1 Nanoformulations Paclitaxel is administered intravenously and has low water solubility

From day 0, vehicle, MTX (7.6 mg/kg, once a week) or Epal (15.5 mg/kg, once a day) were oral administrated

At 10 nM concentration in intestinal cells, KPV cuts NF-B-driven reporter activity significantly compared to IL-1 stimulation alone

It has narrow tight- junctions, no fenestrae, low pinocytotic activity and a continuous basement membrane

Unexpected Ca2+-mobilization of oxaliplatin via H1 histamine receptors

Peripheral sensitization caused by insulin-like growth factor 1 contributes to pain hypersensitivity after tissue injury